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585), for all photon energies considered in this study. 1044 INDEX Nodal, (Continued) endoderm development and, 299300 expression, 266 inhibitors, 281 in organizer formation, 279 related ligands, 310 signaling, 282, 300f, 301, 303304, 306, 310311, 685 Xenopus and, 279 in zebrafish, 266 Nodose ganglion, 593 Noggin, 247, 249, 267, 277, 280, 550, 596, 756, 868, 895, 919 Nos1, 153 Nos2, 153 notail, 375 Notch, 6, 19, 137, 251, 335, 550, 579, 582, 923, 1017 activation, 327328, 329, 331 cell biology of, 319f in DV compartment boundary, 331 expression, 732 lateral inhibition and, 322f ligands, 732 midd, 732 signaling, 253, 254, 330f, 333334, 511, 565566, 639, 688, 730f, 732734, 990, 1009f, 10121014 signaling pathway, 316318, 641f structure of, 317f Notch extracellular domain (NECD), 317, 318319, 335336 Notch intracellular domain (NICD), 317319, 328329, 335336, 1013 Notch receptors, endocytosis and, 320321 NOTCH1, 703 Notch-Delta juxtacrine signaling system, 880, 884, froex Notochord, 879f homology, 122123, 125 in pancreatic endocrine differentiation, 950 precursors, 373 Novel signaling pathway components, 612 Nppa, 350 NP-plexin receptor complexes, 742743 Nr1, 564 Nr2e3, 564 Nr-CAM, 532 NRP1, 247 NRP2, 739 NSCs.
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